ALS: Finding Comfort in Cannabis

Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Patients with ALS suffer from a loss of muscle control that eventually leads to paralysis and difficulty speaking, breathing, and swallowing. While there is no cure for ALS, treatments focus on slowing the progression of the disease and managing symptoms to improve quality of life. Increasingly, patients and clinicians are looking toward medical cannabis as a source of relief.

Clinical Evidence on Cannabis for ALS Symptoms

Cannabis has been studied for its potential in managing several symptoms associated with ALS. The neuroprotective, anti-inflammatory, and pain-relieving properties of cannabinoids may offer symptomatic relief. Muscle spasms, one of the most common and distressing symptoms of ALS, can be debilitating. Cannabis is known to have antispasmodic qualities, which could provide much-needed comfort to patients.

A study in the “American Journal of Hospice and Palliative Medicine” explored cannabis’s efficacy in symptom management for ALS. It found that patients reported cannabis to be moderately to highly effective in providing symptom relief for appetite loss, depression, pain, spasticity, drooling, and weakness (Carter et al., 2010).

Personal Stories of Comfort

John, an ALS patient, shared his experience in a feature by the ALS Association. He turned to medical cannabis after his diagnosis and found that it significantly eased his chronic pain and muscle spasms. John’s story mirrors that of many others who have found that cannabis can make living with ALS more bearable, particularly as conventional treatments for spasticity and pain can have undesirable side effects.

Sarah, another ALS patient, highlighted how cannabis helped her manage not just the physical symptoms, but also the emotional toll of ALS. She credited cannabis with improving her mood and helping her sleep, which she felt was just as important as its physical relief.

Cannabis as a Multi-Symptom Management Strategy

The multifaceted benefits of cannabis may address several symptoms simultaneously, a feature particularly valuable in a multi-symptom condition like ALS. Pain and muscle stiffness, which commonly occur in ALS patients, may be mitigated by the analgesic and muscle relaxant properties of THC and CBD. Furthermore, the potential for cannabis to enhance appetite and reduce weight loss can be vital for patient care, given the muscle wasting that occurs in ALS.

Research and Recommendations

Despite promising anecdotes and preliminary research, there is still much to learn about cannabis’s role in ALS symptom management. Health professionals recommend that ALS patients considering cannabis start with low doses and monitor effects closely, tailoring use to the individual’s symptoms and response to therapy. It’s also crucial for patients to consult with their healthcare team to ensure that cannabis use is coordinated with other aspects of their ALS treatment plan.


While further research is needed to fully understand and optimize cannabis’s role in ALS care, current clinical evidence and personal accounts suggest it may offer symptomatic relief for some patients. As awareness grows and legislation evolves, cannabis could become an integral part of the multidisciplinary approach to ALS, helping patients find comfort and maintain quality of life in the face of this challenging disease.


  1. Carter, G. T., Abood, M. E., Aggarwal, S. K., & Weiss, M. D. (2010). Cannabis and amyotrophic lateral sclerosis: hypothetical and practical applications, and a call for clinical trials. American Journal of Hospice and Palliative Medicine, 27(5), 347-356.

This blog post is for informational purposes only and does not constitute medical advice. It is important to consult with healthcare professionals before starting any new treatment, especially for conditions as complex as ALS.


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